• As with any open label study it is possible

  2019-06-20

  

  As with any open-label study, it is possible that a placebo effect may have contributed to patients analgesia after initiation of the therapy. A randomized placebo-controlled trial would be required to finally prove the high analgesic effect of the loading-dose treatment with Ibandronate in metastat

• br Material and methods br

  2019-06-20

  

  Material and methods Results Discussion Conclusion Financial support Conflicts of interest Introduction Metabolic syndrome comprises a cluster of conditions, including obesity, insulin resistance, hypertension, and abnormal cholesterol levels, which together increase cardiovascu

• Universalisation means reaching all individuals with

  2019-06-20

  

  Universalisation means reaching all individuals with good quality, effective interventions without financial hardship. Coverage matters. Participatory women\'s groups are effective in reducing newborn mortality among poor populations provided they involve about 30% of pregnant women in the populatio

• br In this issue of Tiffany Chao and

  2019-06-20

  

  In this issue of , Tiffany Chao and colleagues present a systematic, comprehensive, and critical assessment of published estimates of the cost-effectiveness of essential surgery, and thus make an important contribution to the published work on the economics of global health interventions. Their he

• By showing the great variability in surgical outcomes across

  2019-06-19

  

  By showing the great variability in surgical outcomes across LMICs, Uribe-Leitz and colleagues have shared with the world instructive knowledge that aids our ongoing advocacy efforts to promote quality in surgical care in resource-limited settings. Ultimately, for destitute sick and injured patients

• Education is part of the foundation for

  2019-06-19

  

  Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pres

• br Case report A year old man with a

  2019-06-19

  

  Case report A 54-year-old man with a surgically repaired DORV was admitted to our hospital due to palpitations and worsened right ventricular heart failure. He had been diagnosed with DORV and had undergone the Blalock Taussig operation at 7 years of age. He underwent the Rastelli operation at 35

• br Discussion SIS is a morphological characteristic

  2019-06-19

  

  Discussion SIS is a morphological characteristic of the basal interventricular septum that protrudes into the LV cavity. This cardiac malformation has generally been considered a natural part of aging without pathophysiological or clinical significance [5,6]. However, several studies demonstrated

• In addition to inducing IKs

  2019-06-19

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• As en una parodia llevada al extremo del absurdo de

  2019-06-19

  

  Así, en una parodia llevada al extremo del absurdo de esta escritura blanca o vacía, Amélie descubre finalmente que los tesoros vivientes no escriben, sus libros son “maquetas empastadas con las hojas en blanco” (55). Tekendogo es un país donde la dictadura se legitima buy KNK437 través de una ritua

• More than structural haemoglobin variants have

  2019-06-19

  

  More than 900 structural haemoglobin variants have been described. Of these more than 100 show high oxygen affinity [2]. Erythrocytosis caused by Hb Ypsilanti was first described in 1967 [3], and the mutation results in substitution of amino 3-Deazaadenosine (β99 Asp→Tyr) involved in the stability

• br Conclusion br Conflict of interest br

  2019-06-19

  

  Conclusion Conflict of interest Introduction Recent trials of the use of implantable electronic devices, including implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-Ds) show survival benefits [1–3]. As a result, implantable electronic d

• The great American epidemiologist Bill Silverman taught us

  2019-06-18

  

  The great American epidemiologist Bill Silverman taught us that the road to hell is paved with good intentions. From 1942, during a 12-year period, more than 10 000 infants were blinded through retinopathy of prematurity because paediatricians recommended a minor increase in the concentration of sup

• br Alegato y ret rica de la violencia en

  2019-06-18

  

  Alegato y retórica de la violencia en la Brevíssima relación de la destruyción de las Indias En el año 1552 fray Bartolomé de las Casas, en Sevilla, se ocupa de dar learn this here now la imprenta ocho de sus principales escritos, entre ellos la Brevíssima relación, compuesta diez años antes: “Y

• Equally important to the scientific findings of Soka

  2019-06-18

  

  Equally important to the scientific findings of Soka and colleagues\' report is the context of the activities—established not as a research study but as a national programme oriented toward health service provision and risk reduction. The programme packaged semen testing with counselling for survivo

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