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The lack of a single identified
2019-06-28

The lack of a single identified correlate of protection for LAIV should not deter future immunogenicity studies in resource-limited settings, especially using systems vaccinology approaches designed to dissect the complex interplay of innate and adaptive pathways following vaccination. John C Victor
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Idelalisib demonstrates a dual mechanism of action by
2019-06-28

Idelalisib demonstrates a dual mechanism of action by inhibiting pro-survival signalling pathways [6], and, like other kinase inhibitors, leads to re-localisation of tumour pka kinase by blocking ingress into and promoting egress out of the lymph node into the blood. Release from the protective lymp
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br In an age when
2019-06-28

In an age when everything from sparrows to toilets has its own international day (March 20 and November 19, respectively, in case you were wondering), it\'s perhaps no surprise that the scholarly publishing (-)-Huperzine A molecular has got in on the act. This week is . Organised by representati
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Although a wealth of studies tracking ODA have
2019-06-28

Although a wealth of studies tracking ODA+ have been done, few have provided in-depth study of how ODA+ in reproductive, maternal, newborn, and child health affects health outcomes, and to what extent the long-term goal of donors has been achieved through aid programmes. This panel dataset opens the
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Introduction This document does not address
2019-06-28

Introduction This document does not address the indications of genetic testing in patients affected by inherited arrhythmias and their family members. Diagnostic, prognostic, and therapeutic implications of the results of genetic testing also are not included in this document because this topic has
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The tumor microenvironment is enriched with EMVs that are
2019-06-28

The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma
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Automated template matching available in some electrophysiol
2019-06-28

Automated template matching, available in some electrophysiology systems, has been used to improve pace matching in the ventricle [13]. We found that using automated analysis improved the resolution of pace mapping, especially with bipolar EGMs. The matching algorithms are relatively simple and not
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Transformation of sanitation related knowledge into routine
2019-06-28

Transformation of sanitation-related knowledge into routine practice is hindered by traditional mindsets and the absence of awareness and an attitude to learn. Poverty has been described as a barrier to following safe hygiene practices. Regular use of footwear is equally important for the prevention
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This trial included patients who met the ICD
2019-06-27

This trial included 1500 patients, who met the ICD criteria for primary prevention (non-ischemic, ischemic, dual chamber ICD or CRT-D). The patients were randomized to 3 arms: (1) conventional therapy: Zone 1(VT) 170bpm, 2.5s delay, Zone 2 (VF) 200bpm, 1s delay; (2) high rate therapy: Zone 1(VT) 170
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The presence or absence of
2019-06-27

The presence or absence of atrial potentials could not be confirmed by the VEGM. Consequently, atrial potentials with atrial event markers could not be differentiated from FFRW or noise activity in the VEGM (Fig. 6). In addition, tiny suspected atrial potentials without any atrial event markers coul
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Lymphocytic infiltrates in thyroid cancer
2019-06-27

Lymphocytic infiltrates in thyroid cancer may suggest a background of chronic lymphocytic thyroiditis. Thyroiditis is characterized by a cellular immune response with dense lymphocytic infiltration of the thyroid gland, as well as by a humoral immune response leading to the production of autoantibod
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The results described thus far suggest that
2019-06-27

The results described thus far suggest that PtAF-induced atrial remodeling combined with acute atrial stretch facilitates anchoring of 3-D scroll waves to the border of atrial pectinate muscle and prolongs their life span in favor of AF maintenance. However, why is it that scroll waves anchor to the
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Common and rare SCN A variants may contribute
2019-06-27

Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian
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Si bien esta amerita un an
2019-06-27

Si bien esta amerita un análisis detallado, me detendré en algunas cuestiones que considero clave para entender el modo en cómo resuelve Vigil la integración del pasado colonial. En primer lugar, aparece ya una clara intención de situar endothelin receptor éste como los orígenes de lo que será la n
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Brasil y Argentina son los dos pa ses que
2019-06-27

Brasil y Argentina son los dos países que comparten fronteras con todos los países restantes del bloque primigenio. Aun así, sus legislaciones abordan el tema en menor profundidad en comparación Mefloquine hydrochloride structure como lo hacen Paraguay y Uruguay. En Brasil, la Ley 11445 es la que re
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